what chemo drugs cause lung damage

These Medications Could Harm Your Lungs - GoodRx Investigating the power of music for dementia. Last medically reviewed on September 21, 2021, Success rates help indicate how effective various treatments are. Accessed Oct. 1, 2019. What Is Transitional Cell Carcinoma (TCC)? https://www.rheumatology.org/I-Am-A/Patient-Caregiver/Treatments/Cyclophosphamide-Cytoxan. See, A fever higher than what your cancer care team has instructed (usually 100.5F -101F or greater (taken by mouth), An allergic reaction, such as swelling of the mouth or throat, severe itching, trouble swallowing, Pain or soreness at the chemo injection site or catheter site, Unusual pain, including intense headaches, Shortness of breath or trouble breathing (If youre having trouble breathing call 911 first. But some times it is permanent. information and will only use or disclose that information as set forth in our notice of If a person plans on having children in the future, some procedures may make this a possibility. Symptoms may not occur until 2-3 months after radiation treatment. Even if you dont feel hungry, its important to continue eating healthy foods. The STAR program for cancer rehabilitation was designed specifically to address symptoms that prevent cancer survivors from enjoying the quality of life they otherwise can. Its common to lose bone mass with age, but some chemo drugs can increase this loss. Some cancer survivors have fatigue for months or even years after finishing treatment. The American Society of Clinical Oncology (ASCO) offers cancer treatment summary forms to store this information. Ask your doctor if the chemo drugs youre getting have long-term effects. Other therapies may also affect the bones and bone density, such as hormonal therapies. Accessed May 17, 2017. Our 24/7 cancer helpline provides support for people dealing with cancer. Some treatments may cause men to experience symptoms similar to menopause. Learn more about cancer-related fatigue. The American Cancer Society medical and editorial content team. (2021). Doctors may use it often for anal, cervical, lung, and bladder, 5FU is a type of chemotherapy drug that can be used for several different types of cancers. Your doctor may use a test called echocardiography, also called an echo. Other conditions may make peripheral neuropathy more likely, such as having other chronic conditions affecting the nerves. Symptoms of bladder irritationmay include pain or urgency with urination, or blood in your urine. In some cases, depending on the reactions your body is having, your doctor may need to adjust the type or dose of chemotherapy. There are also treatments to help relieve side effects. Mathai SC, et al. Raghu G, et al. Table 1 Chemotherapy drugs that have been reported to cause kidney damage in 10% or more of patients Immunotherapy most commonly - Immune checkpoint inhibitors (ICI) are rapidly replacing chemotherapy treatments and have become the standard of care for the . It is not always possible to prevent long-term side effects from chemotherapy. This is a common effect of many cancer treatments, along with skin changes and hair loss . Doctors try to give chemo at levels high enough to treat cancer, while keeping side effects at a minimum. Goldman L, et al., eds. Nearly any cancer treatment can cause late effects. Drugs designed to kill cancer cells, such as methotrexate (Otrexup, Trexall, others) and cyclophosphamide, can also damage lung tissue. Pneumonitis causes symptoms such as chest tightness . Chemotherapy may cause late side effects in the heart for some people, such as: Research from 2017 notes that some side effects like cardiovascular (heart and vessel) complications may not occur until 20 years after cancer treatment. How Do I Talk to My Doctor About Alternative Medicine? Pulmonary fibrosis - Symptoms and causes - Mayo Clinic Most chemotherapy drugscause accelerated bone loss. If we combine this information with your protected Chemotherapy drugs can also cause side effects that don't become evident until months or years after treatment. Drug-induced pulmonary disease: MedlinePlus Medical Encyclopedia This can result in a decreased ability of your kidneys to filter your blood. Fingernail and Toenail Problems During Chemotherapy - Verywell Health Even short delays in cancer treatment can increase a patient's odds of death, and substitute medications may be less effective or more toxic, if they exist at all. When looking at how best to combine chemo drugs, doctors must look at interactions between chemo drugs and other medicines the person is taking, including over-the-counter medicines, vitamins, and supplements. This scarring makes the lungs stiff and harder for people to breathe. Yang Q-J, et al. Some side effects may occur long after treatment is over and linger. Second cancers related to treatment. Ask your doctor for the details of your chemotherapy treatments so that you can make arrangements for work, children, pets or other commitments. Treatments that affect reproductive organs or the endocrine system increase risk of infertility. People who had radiation therapy or surgery to remove lymph nodes may develop lymphedema. 2/2022 This damage may include inflammation, which reduces the amount of oxygen you can absorb, and/or scarring, which reduces the amount of air you can breathe. Some chemotherapy drugs can cause pneumonitis, as can radiation therapy to the lungs. All rights reserved. Interstitial lung disease can be triggered by many different things including airborne toxins in the workplace, drugs and some types of medical treatments. Martinez FJ, et al. Fact Sheet. Chemo brain is usually temporary, but for some people, these changes will be long term or permanent. Some survivors may have a higher risk. Some symptoms may subside with time, and doctors can help a person manage these side effects. Fatigue occurs with chemotherapy treatment but may also linger after treatment. Accessed May 17, 2017. Always check with your doctor first before starting to take a vitamin of any kind, even a simple multivitamin. Chemotherapy will affect each person differently. Chu E, DeVita VT. Nov. 25, 2019. Chemotherapy is used to kill cancer cells in people with cancer. 8 Common Side Effects. In most cases, the causes are unknown. Approach to the adult with interstitial lung disease: Clinical evaluation. Symptoms include lightheadedness, chest pain, and shortness of breath. Accessed May 17, 2017. If feelings of depression persist, look for professional counseling or talk with your doctors. Journal of thoracic and cardiovascular surgery. It is more common in those who had high doses of radiation therapy to the chest. Heart medications. Infertility means not being able to become pregnant or father a child. Kalra R, et al. It may also cause menopause to start right away. Digestion problems. Neutropenic enterocolitis (typhlitis). If you snore loudly and feel tired even after a full night's sleep, you might have sleep apnea. Additionally, your fingernails and toenails may turn yellow and become brittle. We also look at how long the side effects may last and how to prevent them. What Is Chemoradiation and What Types of Cancer Is It Used For? The long-term side effects of this may include an increased risk of dental issues such as cavities and sensitivity. Nevertheless, it's important to see your doctor at the first sign of breathing problems. This can help them identify treatment effects and recommend secondary treatments and precautions for those at a higher risk of bone loss. Some targeted drugs have very few side effects, and others can cause more or more serious problems. Dental and oral health and vision problems. There are also treatments to help relieve side effects. Here, we provide success rates of treatments involving chemotherapy for various, Some common side effects of chemotherapy include infection, bleeding easily, hair loss, and nausea or vomiting. 2017;151:619. Chemotherapy may cause additional side effects in rare cases. Chemotherapy drugs can cause several side effects. It's only very recently that the term "survivorship" was coined, and the long-range physical, emotional, and spiritual aspects of surviving cancer are becoming better understood. More research is needed, but until more is known about the effects of vitamins on chemo, keep these points in mind: Because your cancer care team will give you lots of information about side effects, you might be more aware of physical changes. American College of Rheumatology. Everything You Need to Know About Oral Chemotherapy, What Happens to Your Body During Chemo? If you are already pregnant when you receive a cancer diagnosis, you still have options. In: Goldman-Cecil Medicine. Chemotherapy-induced pulmonary complications in cancer: Significance of High doses of radiation therapy to the head and neck area may change tooth development. Symptoms include chest pain and shortness of breath. The Lancet Respiratory Medicine. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). He or she may check your heart function and watch for damage during and after treatment. Cancer survivors should have regular physical examinations and hearing tests after treatment to check for these effects. Some chemo drugs cause long-term side effects, like heart or nerve damage or fertility problems. You may be able to change your medicine or treatment schedule. MNT is the registered trade mark of Healthline Media. 2015;149:1394. 2023 Healthline Media UK Ltd, Brighton, UK. Your healthcare team may also be able to suggest a local cancer support group where you can speak with others undergoing cancer treatment. Fatigue. Chemotherapy drugs can damage sperm and can also harm the fetus if given during pregnancy, possibly leading to birth defects. What to know about preparing for chemotherapy. Some survivors may have a higher risk. Advertising revenue supports our not-for-profit mission. These include: Hearing loss from high doses of chemotherapy, especially drugs like cisplatin (multiple brand names), Increased risk of stroke from high doses of radiation to the brain, Nervous system side effects, including damage to the nerves outside the brain and spinal cord, called peripheral neuropathy. Below is a list of the more common late effects. BMJ. Understanding Peripheral Neuropathy All rights reserved worldwide, Long-Term Side Effects of Cancer Treatment, Living with Cancer While Receiving Long-Term Treatment, men to experience symptoms similar to menopause. If you have been treated with Adriamycin, your healthcare provider may recommend a MUGA scan to monitor your heart. Together you can decide what's right for you. 11 long-term side effects of chemotherapy - Medical News Today Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. Weaver M.D. Talk with your doctor right away if you have any of these symptoms: Congestive heart failure (CHF) is weakening of the heart muscle. Make regular appointments with your dentist and eye doctor. Long-Term Side Effects of Radiation Therapy, Aggressive Neuroendocrine Colon and Rectum Tumors, An Overview of Squamous Cell Carcinoma in the Lungs. Certain types of chemo also impact your mucosa more than others. Mayo Clinic does not endorse companies or products. The severity of the damage may depend on: How much of the lung was exposed to radiation; The total amount of radiation administered; Whether chemotherapy also was used; The presence of underlying lung disease; Medications. Osteoporosis(thinning of the bones) is the most common late effect of chemotherapy. AskMayoExpert. Chemo Brain. Removing it is linked with a higher risk of infections. Cancer.Net. Make sure you know how to reach someone on your team any time, including after hours, weekends, and holidays. Interstitial (in-tur-STISH-ul) lung disease describes a large group of disorders, most of which cause progressive scarring of lung tissue. One example is phantom limb pain. Menstrual periods may stop completely for other women. Many people find that their "new normal" is not what they would like, and feel frustrated by the symptoms. Or it may be a separate symptom. But because these drugs travel throughout the body, they can affect normal, healthy cells that are fast-growing, too. (2020). Do reading, puzzles, and similar activities really stave off dementia? Steroids are often given along with chemotherapy or for symptoms and side effects related to cancer. It is important to discuss any side effects youre experiencing with your doctor.

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